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Reactivity Documentation

Isocyanates and Isothiocyanates

mixed with

Aldehydes

Summary

Details

Isocyanates and Isothiocyanates is a reactive group.
Aldehydes is a reactive group.

Reactivity Predictions (for each pair of reactive groups)

Aldehydes mixed with
Isocyanates and Isothiocyanates

Hazard Predictions

Acetaldehyde reacts violently with isocyanates (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 5).

There is much literature on the condensation reaction between isocyanates and aldehydes, however there is little to support that it will occur at room temperature without catalyst present. Most require strong bases or metallic catalysts and heat to initiate the reaction.