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Hazard Predictions

• Polymerization hazard: Polymerization reaction may become intense and may cause pressurization

Isocyanates react readily with acids at room temperature (Richter, Reinhard H., Ralph D. Priester Jr. 2000. Isocyanates, Organic. In Kirk-Othmer Encyclopedia of Chemical Technology. John Wiley & Sons, Inc. (Online)).

Acids initiate polymerization of isocyanates, particularly when other reactants are present (Personal communication with chemical industry experts). Caution should be used before proceeding. Further research of comparable examples in the literature or very small scale, carefully controlled experiments may be needed to fully assess compatibility.