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Hazard Predictions

• Generates gas: Reaction liberates gaseous products and may cause pressurization
• Generates heat: Exothermic reaction at ambient temperatures (releases heat)
• Toxic: Reaction products may be toxic

The combination of acyl halides and alkynes with attached hydrogen atoms may result in exothermic addition across the C-C triple bond and formation of HX gas (Predicted). Caution should be used before proceeding. Further research of comparable examples in the literature or very small scale, carefully controlled experiments may be needed to fully assess compatibility. The generation of gases may be rather slow, however confinement may lead to dangerous conditions.

Potential Gas Byproducts

• Hydrogen Halide (HX)
• Acid Fumes